TEAM Mammalian Cell Designers’ Laboratory

MISSION

Our mission is to engineer next-generation mammalian cell factories
for the production of complex biotherapeutics.
By integrating synthetic biology, genome engineering, and autonomous experimentation,
we aim to transform cell line development from empirical optimization into a predictive engineering discipline.

Principal Investigator

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Principal Investigator 목록
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Jae Seong Lee, Ph.D.

Associate Professor
Graduate School of Engineering Biology
Korea Advanced Institute of Science and Technology (KAIST)

Google scholar link

Research Gate link
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  • Academic Positions

    1. 2025 – Present Associate Professor, Graduate School of Engineering Biology
      KAIST, South Korea
    2. 2021 – 2025 Associate Professor, Department of Molecular Science and Technology
      Advanced College of Bio-Convergence Engineering
      Ajou University, South Korea
    3. 2023 – 2024 Visiting Scholar, Departments of Pediatrics and Bioengineering
      University of California San Diego, USA
      Host: Prof. Nathan E. Lewis
    4. 2017 – 2021 Assistant Professor, Department of Molecular Science and Technology
      Department of Applied Chemistry and Biological Engineering
      Ajou University, South Korea
    5. 2016 – 2017 Research Scientist, The Novo Nordisk Foundation Center for Biosustainability
      Technical University of Denmark (DTU), Denmark
    6. 2013 – 2015 Postdoctoral Researcher, The Novo Nordisk Foundation Center for Biosustainability
      DTU, Denmark
      Mentors: Prof. Michael J. Betenbaugh and Dr. Helene Faustrup Kildegaard
    7. 2012 – 2013 Postdoctoral Researcher, Department of Biological Sciences
      KAIST, South Korea
      Mentor: Prof. Gyun Min Lee
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  • Education

    1. 2012 Ph.D., Biological Sciences
      KAIST, South Korea
      Dissertation: Analysis and Engineering of Autophagy in CHO Cells under Stressful Culture Conditions
      Advisor: Prof. Gyun Min Lee
    2. 2007 B.S., Biological Sciences, Magna Cum Laude
      KAIST, South Korea
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  • Research Interests

    1. Mammalian Synthetic Biology
    2. Genome Engineering for Mammalian Cells
    3. Autonomous Cell Engineering Platforms
    4. Biopharmaceutical Manufacturing